Barriere H, Berger M, Billaudel S
Sem Hop. 1976 Nov 16;52(39):2215-20.
Two characteristic cases encountered in young adults led the authors to present the hand foot and mouth syndrome. They report the characteristic distribution and vesicular appearance of the lesions. The course was benign. The viral origin of the disease was more or less easily confirmed by cell culture, inoculation in new born mice and demonstration of antibodies. Usually the virus was a Coxackie A 16. However in one of the authors cases, an Echo 11 was demonstrated. The apparent rareness of the disease may be explained by lack of recognition.
两名年轻成人身上出现的典型病例促使作者介绍手足口综合征。他们报告了病变的特征性分布和水疱表现。病程呈良性。通过细胞培养、接种新生小鼠以及抗体检测，疾病的病毒起源或多或少得以轻松确认。通常该病毒为柯萨奇A16型。然而，在作者的一个病例中，检测出了埃可11型病毒。这种疾病看似罕见，可能是由于认识不足所致。
