Vayisoglu Yusuf, Ozcan Cengiz, Polat Ayse, Delialioglu Nuran, Gorur Kemal
Mersin University, School of Medicine, Department of Otorhinolaryngology, Mersin, Turkey.
Int J Pediatr Otorhinolaryngol. 2008 Oct;72(10):1497-501. doi: 10.1016/j.ijporl.2008.06.018. Epub 2008 Aug 8.
Evaluation of the possible relationship between chronic adenotonsillitis and Helicobacter pylori (HP).
The study was performed prospectively on 91 pediatric patients who underwent tonsillectomy, adenoidectomy or adenotonsillectomy due to chronic tonsillitis and/or adenoiditis. The adenotonsillectomy specimens were examined for HP colonization by rapid urease test (RUT) and immunohistochemical evaluation. Before surgery, anti-HP IgG and IgA antibody titers were detected by enzyme linked immunosorbent assay (ELISA) test in venous blood samples of the patients.
The RUT was positive in only two of the adenoidectomy specimens (2.2%) and in none of the tonsillectomy specimens. A positive result was not detected in any tonsillectomy specimens using immunohistochemical examination. Serum IgG antibody was positive in 21 (23%) patients, IgA antibody was detected in 7 (7.69%) patients and both tests were positive only in 3 (3.29%) patients.
The results of this study suggested that HP would not colonize in tonsil tissue of patients with chronic tonsillitis.
评估慢性腺扁桃体炎与幽门螺杆菌（HP）之间可能存在的关系。
本研究前瞻性纳入了91例因慢性扁桃体炎和/或腺样体炎接受扁桃体切除术、腺样体切除术或腺扁桃体切除术的儿科患者。通过快速尿素酶试验（RUT）和免疫组化评估对腺扁桃体切除标本进行HP定植检测。手术前，采用酶联免疫吸附测定（ELISA）法检测患者静脉血样本中的抗HP IgG和IgA抗体滴度。
仅2例腺样体切除标本的RUT呈阳性（2.2%），扁桃体切除标本均为阴性。免疫组化检查在任何扁桃体切除标本中均未检测到阳性结果。血清IgG抗体阳性的患者有21例（23%），IgA抗体检测阳性的患者有7例（7.69%），两项检测均阳性的患者仅3例（3.29%）。
本研究结果表明，HP不会在慢性扁桃体炎患者的扁桃体组织中定植。
