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计算机动态监测在药物依赖女性中的可行性和有效性

Feasibility and validity of computerized ambulatory monitoring in drug-dependent women.

作者信息

Johnson Elizabeth I, Barrault Marion, Nadeau Louise, Swendsen Joel

机构信息

National Center for Scientific Research (CNRS 5231), 146 rue Léo Saignat, 33076 Bordeaux Cedex, France.

出版信息

Drug Alcohol Depend. 2009 Jan 1;99(1-3):322-6. doi: 10.1016/j.drugalcdep.2008.06.010. Epub 2008 Aug 9.

DOI:10.1016/j.drugalcdep.2008.06.010
PMID:18692969
Abstract

AIM

To examine the feasibility and validity of computerized ambulatory monitoring in drug-dependent women.

METHOD

61 women recruited from public substance abuse treatment centers in Montreal, Canada participated in the current study, 84% of whom reported past 30-day polysubstance use. Mood states, craving, and drug use were assessed by standard clinical instruments and by electronic interviews during 7-days of computerized ambulatory monitoring. Feasibility was assessed by examining compliance with intensive monitoring and equipment loss. Concurrent validity was assessed by examining the degree of correspondence of ambulatory data on craving, mood, and substance use with clinic-based assessments of similar constructs.

RESULT

Participants completed an average 80% of all electronic assessments and no data collection devices were lost or stolen. Relationships among mood, stress, consumption, and craving assessed in the electronic interviews conformed to well-established patterns, and evidence of concurrent validity were found between scores from standard clinical instruments and similar constructs in daily life. Center for Epidemiological Studies-Depression Scale (CESD) scores were positively related to sad mood reported during the electronic interviews (p=0.001) and negatively related to happy mood states (p<0.001), explaining approximately 20% of the variance in each mood state. ASI drug use severity scores were positively associated with craving (p<0.001) and substance use (p<0.001), and explained 46% and 30% of these outcomes, respectively.

CONCLUSION

Computerized ambulatory monitoring is a feasible and valid data collection strategy in drug-dependent individuals.

摘要

目的

探讨计算机化动态监测在药物依赖女性中的可行性和有效性。

方法

从加拿大蒙特利尔的公共药物滥用治疗中心招募了61名女性参与本研究,其中84%的人报告在过去30天内使用多种药物。在7天的计算机化动态监测期间,通过标准临床工具和电子访谈对情绪状态、渴望程度和药物使用情况进行评估。通过检查对密集监测的依从性和设备丢失情况来评估可行性。通过检查动态监测数据中关于渴望、情绪和物质使用与基于诊所的类似构念评估之间的对应程度来评估同时效度。

结果

参与者平均完成了所有电子评估的80%,且没有数据收集设备丢失或被盗。电子访谈中评估的情绪、压力、药物使用和渴望之间的关系符合既定模式,并且在标准临床工具的得分与日常生活中类似构念之间发现了同时效度的证据。流行病学研究中心抑郁量表(CESD)得分与电子访谈中报告的悲伤情绪呈正相关(p = 0.001),与愉快情绪状态呈负相关(p < 0.001),分别解释了每种情绪状态中约20%的变异。成瘾严重程度指数(ASI)药物使用严重程度得分与渴望(p < 0.001)和物质使用(p < 0.001)呈正相关,分别解释了这些结果的46%和30%。

结论

计算机化动态监测是药物依赖个体中一种可行且有效的数据收集策略。

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