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[阿根廷出生体重的长期趋势(1992 - 2002年):一项基于人群的研究]

[Secular trend of birth weight in Argentina (1992-2002): a population based study].

作者信息

Grandi Carlos, Dipierri José E

机构信息

Consejo de Investigación en Salud, Maternidad Sardá, Buenos Aires.

出版信息

Arch Argent Pediatr. 2008 Jun;106(3):219-25. doi: 10.1590/S0325-00752008000300006.

Abstract

INTRODUCTION

Birth weight (BW) is considered an important measure of the health status of a population. Objectives. 1) to assess secular trends in average BW, low birth weight (LBW,<2.500 g), very low birth weight (VLBW, < 1.500 g) and BW > or = 3.000 g of liveborn infants in Argentina; 2) calculate risks of LBW, VLBW and > or = 3.000 g; 3) influence of underreported birth weight.

MATERIAL AND METHODS

In this national-based study 7.113.931 liveborn infants born in Argentina from 1992 to 2002 were included. BW was assessed from the National Ministry of Public Health. Annuals mean BW and residual distribution (RD) following the Wilcox-Russell approach were calculated, and also LBW, VLBW and > or =3.000 g proportions.

RESULTS

A decrease of 32 g in average BW (p= 0.577) and 24 g between 2000 and 2002 (p <0.001) was observed. RD reached 4%. The significant increase in LBW (12%, p= 0.034) and VLBW (26%, p= 0.002) proportions was paralleled by a reduction of 3.6% in BW > or =3.000 g (p= 0.011, average 75.2%). Risks of being LBW and VLBW were 1.13 (95% CI 1.12-1.15) and 1.30 (1.25-1.35), respectively; for BW > or =3.000 g was 0.86 (95% CI 0.85-0.87). No significant correlations between underreported BW and proportions of LBW (r= 0.10) or VLBW (r= 0.01) were observed.

CONCLUSION

A negative secular trends of BW was observed, all categories of LBW and VLBW were increased, BW > 3.000 g was diminished and under-reported BW did not influenced these results.

摘要

引言

出生体重(BW)被视为衡量人群健康状况的一项重要指标。目标:1)评估阿根廷活产婴儿平均出生体重、低出生体重(LBW,<2500克)、极低出生体重(VLBW,<1500克)以及出生体重≥3000克的长期趋势;2)计算低出生体重、极低出生体重以及出生体重≥3000克的风险;3)出生体重报告不足的影响。

材料与方法

在这项基于全国范围的研究中,纳入了1992年至2002年在阿根廷出生的7113931名活产婴儿。出生体重数据来自国家公共卫生部。按照威尔科克斯 - 拉塞尔方法计算年度平均出生体重和残差分布(RD),以及低出生体重、极低出生体重和出生体重≥3000克的比例。

结果

观察到平均出生体重下降了32克(p = 0.577),2000年至2002年间下降了24克(p <0.001)。残差分布达到4%。低出生体重比例显著增加(12%,p = 0.034),极低出生体重比例显著增加(26%,p = 0.002),同时出生体重≥3000克的比例下降了3.6%(p = 0.011,平均为75.2%)。低出生体重和极低出生体重的风险分别为1.13(95%置信区间1.12 - 1.15)和1.30(1.25 - 1.35);出生体重≥3000克的风险为0.86(95%置信区间0.85 - 0.87)。未观察到出生体重报告不足与低出生体重比例(r = 0.10)或极低出生体重比例(r = 0.01)之间存在显著相关性。

结论

观察到出生体重呈负向长期趋势,各类低出生体重和极低出生体重有所增加,出生体重>3000克有所减少,且出生体重报告不足并未影响这些结果。

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