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Synthesis and biological evaluation of novel selenonucleosides.

作者信息

Chen Yao, Peng Yingdan, Zhang Jiancun, Fu Lei

机构信息

School of Pharmacy, Shanghai Jiaotong University, Shanghai, PR China.

出版信息

Nucleosides Nucleotides Nucleic Acids. 2008 Aug;27(8):1001-8. doi: 10.1080/15257770802088803.

DOI:10.1080/15257770802088803
PMID:18696368
Abstract

A series of novel selenonucleoside analogues with 1,4-oxaselenane as the carbohydrate fragment has been synthesized from their corresponding dimesylated seconucleosides treated with NaHSe solution and subsequent deprotection. The synthesized selenonucleoside analogues were evaluated as potential antitumor agents.

摘要

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