Potisat Somkiat, Srisubat Attasit, Krairttichai Udom, Jongsareejit Amporn
Institute of Medical Research and Technology Assessment, Department of Medical Services, Ministry of Public Health, Nonthaburi, Thailand.
J Med Assoc Thai. 2008 Jun;91(6):846-51.
Study the association between microalbuminuria and diabetic retinopathy in type 2 diabetic patients.
A cross-sectional analytic study of 1,111 cases with type 2 diabetic patients recruited from seven public hospitals, between June and December 2006 was performed
Two hundred eighty six subjects (79 males and 207 females) with urine dipsticks for microalbuminuria detection tested positive at least 2 of the 3 morning urine samples within 6 months. They were divided into 2 equal groups, micro- and normoalbuminuria based on quantity of albumin. Indirect ophthalmologic examination of all subjects' eyes for diabetic retinopathy was performed by ophthalmologists (retinal specialists). The present study showed that the proportion of diabetic retinopathy was 19.6% (28/143) and 12.6% (18/ 143) in micro- and normoalbuminuric groups, respectively. The difference of proportion between the groups was 7% but was statistically not significant (p = 0.108).
Microalbuminuria detected using urine dipstick was not cross-sectionaly associated with diabetic retinopathy in type 2 diabetic patients.
研究2型糖尿病患者微量白蛋白尿与糖尿病视网膜病变之间的关联。
对2006年6月至12月期间从7家公立医院招募的1111例2型糖尿病患者进行横断面分析研究。
286名受试者（79名男性和207名女性）在6个月内3次晨尿样本中至少有2次尿微量白蛋白检测试纸检测呈阳性。根据白蛋白量将他们分为两组，微量白蛋白尿组和正常白蛋白尿组，每组人数相等。眼科医生（视网膜专家）对所有受试者的眼睛进行间接眼底检查以诊断糖尿病视网膜病变。本研究表明，微量白蛋白尿组和正常白蛋白尿组的糖尿病视网膜病变比例分别为19.6%（28/143）和12.6%（18/143）。两组之间的比例差异为7%，但无统计学意义（p = 0.108）。
使用尿试纸检测的微量白蛋白尿与2型糖尿病患者的糖尿病视网膜病变在横断面研究中无关联。
