Jitmuang Anupop
Internal Medicine Unit, Nan Hospital, Nan, Thailand.
J Med Assoc Thai. 2008 Jun;91(6):931-6.
Primary actinomycotic endocarditis is extremely rare. The author reported a case who suffered from endocarditis due to Actinomyces georgiae which the portal of entry for the organism could not be determined The author also reviewed the literature which described similar conditions. In addition, to the author's knowledge, there have been no reported cases of actinomyces georgiae endocarditis. Thus, this is the first report in the world. Clinical features of this rare condition are indistinguishable from other bacterial endocarditis. Actinomyces spp. is usually susceptible to a wide range of antibiotics, and endocarditis caused by this genus needs a prolonged course of antimicrobial treatment. However the optimal duration of therapy is still unknown. Prognosis is good with early detection and proper management.
原发性放线菌性心内膜炎极为罕见。作者报告了一例因佐治亚放线菌导致心内膜炎的病例，该病菌的侵入途径无法确定。作者还回顾了描述类似情况的文献。此外，据作者所知，此前尚无佐治亚放线菌性心内膜炎的病例报告。因此，这是世界上首例报告。这种罕见病症的临床特征与其他细菌性心内膜炎难以区分。放线菌属通常对多种抗生素敏感，由该属病菌引起的心内膜炎需要较长疗程的抗菌治疗。然而，最佳治疗时长仍不明确。早期发现并妥善处理，预后良好。
