Rudigoz R C, Thomé Saint-Paul M, Gindre T, de Rochambeau B, Gaucherand P, Wong A
Service de Gynécologie-Obstétrique, Hôpital de la Croix-Rousse, Lyon.
J Gynecol Obstet Biol Reprod (Paris). 1991;20(3):436-42.
The authors carried out a combined study using Doppler Flow Studies of the umbilical and fetal anterior cerebral arteries in 26 pregnancies which were complicated by maternal hypertension. Using the ratio between the cerebral and the umbilical blood flow it may be possible to diagnose intra-uterine growth retardation more accurately than using classical measurements. An inversion of the ratio between the cerebral and the umbilical flows has a great prognostic value with a sensibility of 91.6%, a specificity of 87.5% and a positive predictive value of 84.6% with a negative predictive value of 93.13%. There may however quite often be a lengthy interval of time between the appearance of change in the ratio and the appearance of fetal distress, so that this sign can only be one indication for delivery of the fetus.
作者对26例并发母亲高血压的妊娠进行了一项联合研究，采用了脐动脉和胎儿大脑前动脉的多普勒血流研究。利用脑血流与脐血流的比值，可能比使用传统测量方法更准确地诊断宫内生长迟缓。脑血流与脐血流比值的倒置具有很大的预后价值，敏感度为91.6%，特异度为87.5%，阳性预测值为84.6%，阴性预测值为93.13%。然而，在比值变化出现与胎儿窘迫出现之间可能经常有一段较长的时间间隔，因此这个体征只能作为胎儿分娩的一个指征。
