双致手性离子液体的设计与合成及其作为不对称Baylis-Hillman反应溶剂的应用。

Design and synthesis of bistereogenic chiral ionic liquids and their use as solvents for asymmetric Baylis-Hillman reactions.

作者信息

Garre Satish, Parker Erica, Ni Bukuo, Headley Allan D

机构信息

Department of Chemistry, Texas A & M-University-Commerce, Commerce, TX 75429-3001, USA.

出版信息

Org Biomol Chem. 2008 Sep 7;6(17):3041-3. doi: 10.1039/b808502a. Epub 2008 Jul 21.

DOI:10.1039/b808502a

PMID:18698459

Abstract

Three novel chiral ionic liquids (CILs) containing two chiral centers in the side chain bonded to the 2-position of the imidazolium cation and different anions have been synthesized, characterized and used as chiral solvents for asymmetric Baylis-Hillman (BH) reactions; good yields and fair enantioselectivities were obtained.

摘要

合成了三种新型手性离子液体（CILs），其侧链含有两个手性中心，与咪唑阳离子的2位相连且带有不同阴离子，对其进行了表征，并用作不对称Baylis-Hillman（BH）反应的手性溶剂；获得了良好的产率和中等的对映选择性。