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锯齿状脂质小管

Zigzag lipid tubules.

作者信息

Zhao Yue, Fang Jiyu

机构信息

Advanced Materials Processing and Analysis Center and Department of Mechanical, Materials, and Aerospace Engineering, University of Central Florida, Orlando, Florida 32816, USA.

出版信息

J Phys Chem B. 2008 Sep 4;112(35):10964-8. doi: 10.1021/jp804793c. Epub 2008 Aug 12.

DOI:10.1021/jp804793c
PMID:18698706
Abstract

We report a method based on poly(dimethylsiloxane) (PDMS) stamp-assisted moving contact line to bend lipid tubules into zigzags on glass substrates. Atomic force microscopy (AFM) reveals that the zigzag lipid tubules buckle at the bent sites. The measurements of buckling heights as a function of bending angles suggest a gradual buckling mode. By imaging the zigzag tubules with AFM under different loading forces, we study the correlation between the loading force and the tubule compression. The reduced stiffness at the buckling sites of zigzag tubules suggests that lipid molecules are reorganized during the gradual buckling.

摘要

我们报告了一种基于聚二甲基硅氧烷(PDMS)印章辅助移动接触线的方法,用于在玻璃基板上将脂质微管弯曲成之字形。原子力显微镜(AFM)显示,之字形脂质微管在弯曲部位发生屈曲。屈曲高度随弯曲角度的测量结果表明存在一种渐进屈曲模式。通过在不同加载力下用AFM对之字形微管进行成像,我们研究了加载力与微管压缩之间的相关性。之字形微管屈曲部位刚度的降低表明,在渐进屈曲过程中脂质分子发生了重组。

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