Vaccaro Mario, Guarneri Fabrizio, Barbuzza Olga, Guarneri Claudio
University of Messina. Institute of Dermatology.
Dermatol Online J. 2008 Feb 28;14(2):12.
A 42-year-old woman presented with complaints of rapidly progressing thickening and yellowish discoloration of the nails for the past 24 months. All nails were affected and fingernails were more thickened than toenails. Her palms and soles were normal. Keratosis pilaris, palmoplantar blistering, hyperhidrosis, leukokeratosis, alopecia, dental malformation, corneal abnormalities and epidermoid cysts were absent. This patient has pachyonychia congenita tarda with clinical manifestations limited to nail involvement.
一名42岁女性，主诉在过去24个月中指甲迅速增厚并变黄。所有指甲均受累，且手指甲比脚趾甲增厚更明显。她的手掌和脚底正常。无毛发角化病、掌跖水疱、多汗症、白色角化病、脱发、牙齿畸形、角膜异常和表皮样囊肿。该患者患有迟发性先天性厚甲症，临床表现仅限于指甲受累。
