Kagoshima Kaie, Imai Hideaki, Nagaki Tomohito, Nakamura Mitsunobu, Kazama Ken, Yoshimoto Yuhei
Department of Neurosurgery, Gunma University Graduate School of Medicine, Maebashi-shi, Gunma, Japan.
No Shinkei Geka. 2008 Aug;36(8):703-7.
Intratumoral bleeding from a meningioma is very rare. We herein report a case of a foramen magnum meningioma which presented in association with intratumoral bleeding. A 49-year-old female who had been suffering from occipital headache and shoulder pain on neck motion was referred to our hospital to undergo treatment for a tumor located in the posterior fossa. Magnetic resonance imaging (MRI) demonstrated a foramen magnum meningioma which originated at the lower clivus and extended to the C2 level of the vertebral column. Marked compression and distortion of the medulla oblongata and spinal cord was also noted. Surgery was therefore planned. The patient thereafter suffered from a sudden onset of headache, vomiting and hoarseness, and was transferred to our hospital. A computed tomography (CT) showed intratumoral bleeding, which extended to the subarachnoid space and the fourth ventricle. The tumor, as well as the massive hematoma, were both immediately removed. The histological diagnosis was meningothelial meningioma. We also reviewed the pertinent literature and propose the possible mechanism for such tumor bleeding in this particular location in which the blockage of the cerebrospinal fluid caused a craniovertebral pressure gradient, which thus resulted in intratumoral bleeding.
脑膜瘤的瘤内出血非常罕见。我们在此报告一例枕骨大孔脑膜瘤伴瘤内出血的病例。一名49岁女性,因枕部头痛及颈部活动时肩部疼痛前来我院就诊,拟对其位于后颅窝的肿瘤进行治疗。磁共振成像(MRI)显示为枕骨大孔脑膜瘤,起源于斜坡下部,延伸至脊柱C2水平。还发现延髓和脊髓明显受压及变形。因此计划进行手术。此后患者突然出现头痛、呕吐和声音嘶哑,并被转至我院。计算机断层扫描(CT)显示瘤内出血,出血延伸至蛛网膜下腔和第四脑室。肿瘤及大量血肿均立即被切除。组织学诊断为脑膜内皮型脑膜瘤。我们还回顾了相关文献,并提出了这种特殊部位肿瘤出血的可能机制,即脑脊液梗阻导致颅颈压力梯度,从而引起瘤内出血。