Sunada I, Nakabayashi H, Matsusaka Y, Yamamoto S
Department of Neurosurgery, Saiseikai Ibaraki Hospital, Osaka, Japan.
Radiat Med. 1998 Nov-Dec;16(6):483-6.
A 48-year-old woman presented with sudden left hemiplegia with headache, which deteriorated two days later. CT scan showed repeated intratumoral and subdural hemorrhages. Magnetic resonance imaging showed a parasagittal tumor infiltrating into the superior sagittal sinus, with intratumoral hemorrhage and acute subdural hematoma in the interhemispheric fissure. The intratumoral hematoma had several different intensities, which indicated repeated hemorrhages. The subdural hematoma and the tumor were removed via frontoparietal craniotomy. The histological diagnosis was fibrous-type meningioma with a high Ki-67 labeling index (6.7). As there were tumor cells within the subdural hematoma, it seemed to have resulted from tumoral hemorrhage. A high index of cell proliferation may indicate some mechanism responsible for hemorrhage in malignant tumor.
一名48岁女性因突发左侧偏瘫伴头痛就诊,两天后病情恶化。CT扫描显示肿瘤内及硬膜下反复出血。磁共振成像显示矢状窦旁肿瘤浸润至上矢状窦,肿瘤内出血,大脑镰间裂有急性硬膜下血肿。肿瘤内血肿有几种不同强度,提示反复出血。通过额顶开颅术切除硬膜下血肿和肿瘤。组织学诊断为纤维型脑膜瘤,Ki-67标记指数较高(6.7)。由于硬膜下血肿内有肿瘤细胞,似乎是肿瘤出血所致。高细胞增殖指数可能提示恶性肿瘤出血的某种机制。