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无麻黄碱西纳屈灵所致血管痉挛和中风:病例报告

Vasospasm and stroke attributable to ephedra-free xenadrine: case report.

作者信息

Holmes Robert O, Tavee Jinny

机构信息

Walter Reed Army Medical Center, Silver Spring, MD 20910, USA.

出版信息

Mil Med. 2008 Jul;173(7):708-10. doi: 10.7205/milmed.173.7.708.

DOI:10.7205/milmed.173.7.708
PMID:18700609
Abstract

Following the 2004 ban of ephedra, which was linked to several cases of stroke and myocardial infarction, manufacturers have marketed "ephedra-free" weight loss products that include the active ingredient synephrine. Despite the lack of data on safety and efficacy, synephrine is touted by its promoters as a "safe" alternative to ephedra and is often combined with caffeine, as in the supplement Xenadrine-EFX. We report a case of left middle cerebral artery vasopasm and stroke in a young healthy patient in the setting of Xenadrine-EFX use.

摘要

2004年麻黄碱被禁,此前它与多起中风和心肌梗死病例有关,此后制造商开始推销不含麻黄碱的减肥产品,这些产品含有活性成分辛弗林。尽管缺乏关于安全性和有效性的数据,但辛弗林的推广者宣称它是麻黄碱的“安全”替代品,并且常与咖啡因混合使用,比如在Xenadrine-EFX补充剂中。我们报告了一名年轻健康患者在使用Xenadrine-EFX时发生左大脑中动脉血管痉挛和中风的病例。

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Vasospasm and stroke attributable to ephedra-free xenadrine: case report.无麻黄碱西纳屈灵所致血管痉挛和中风:病例报告
Mil Med. 2008 Jul;173(7):708-10. doi: 10.7205/milmed.173.7.708.
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Suspected adverse reactions associated with herbal products used for weight loss: a case series reported to the Italian National Institute of Health.怀疑与用于减肥的草药产品相关的不良反应:向意大利国家卫生研究所报告的一系列病例。
Eur J Clin Pharmacol. 2011 Mar;67(3):215-24. doi: 10.1007/s00228-010-0981-4. Epub 2011 Jan 18.