胸腺瘤合并低丙种球蛋白血症（古德综合征）患者的痴呆症

de Jesus Nelson Pedro Ferreira, Carvalho Patrícia Margarida Serra, Dias Florbela Maria Grilo, Gaspar Elsa Maria Filipe, de Moura José Júlio Alves

Hospitais da Universidade Coimbra, Serviço de Medicina II, Av, Bissaya Barreto e Praceta Prof, Mota Pinto, 3000-075, Coimbra, Portugal.

Cases J. 2008 Aug 13;1(1):90. doi: 10.1186/1757-1626-1-90.

Good's syndrome is extremely rare and refers to an acquired B and T cell immunodeficiency in thymoma patients. The authors of this article present a case report of a 75-year-old, caucasian male patient previously subjected to examinations for secondary dementia and recurrent infections, which revealed paraneoplastic syndrome arose from thymoma. He underwent thymectomy, while his immunodeficiency syndrome sustained with frequent opportunistic infections, constantly requiring intravenous immunoglobulin treatment.

古德综合征极为罕见，指胸腺瘤患者出现的获得性B细胞和T细胞免疫缺陷。本文作者报告了一例75岁的白种男性患者，该患者此前因继发性痴呆和反复感染接受检查，结果显示为胸腺瘤引发的副肿瘤综合征。他接受了胸腺切除术，但其免疫缺陷综合征仍持续存在，频繁发生机会性感染，持续需要静脉注射免疫球蛋白治疗。