Carr Warner W, Nelson Michael R, Hadley James A
Allergy and Asthma Associates of Southern California, Mission Viejo, California 92691, USA.
Allergy Asthma Proc. 2008 Jul-Aug;29(4):349-57. doi: 10.2500/aap.2008.29.3145.
Allergic rhinitis affects more than 40 million Americans, with estimated costs reaching $5.3 billion annually. The global impact includes negative effects on quality of life (QOL), sleep, diminished work productivity, and exacerbation of comorbid conditions. An accurate diagnosis of allergic or nonallergic rhinitis is needed before selecting optimal treatment, which can include antihistamines, decongestants, intranasal corticosteroids, immunotherapy, and anticholinergics. It is also important to understand that pharmacologic properties of these different interventions may affect patient satisfaction, compliance, and overall clinical response. This article reviews currently available therapies for allergic rhinitis with a focus on improving patient outcomes.
变应性鼻炎影响着超过4000万美国人，估计每年花费达53亿美元。其全球影响包括对生活质量（QOL）、睡眠产生负面影响，工作效率降低，以及合并症加重。在选择最佳治疗方法之前，需要准确诊断变应性或非变应性鼻炎，最佳治疗方法可包括抗组胺药、减充血剂、鼻内皮质类固醇、免疫疗法和抗胆碱能药。同样重要的是要明白，这些不同干预措施的药理特性可能会影响患者的满意度、依从性和总体临床反应。本文综述了目前可用的变应性鼻炎治疗方法，重点是改善患者的治疗效果。
