Ferguson B J
Department of Otolaryngology-Head and Neck Surgery, University of Pittsburgh Medical Center, Pennsylvania, USA.
Otolaryngol Clin North Am. 1998 Feb;31(1):91-110. doi: 10.1016/s0030-6665(05)70032-3.
This article provides guidelines for pharmacotherapy to maximize symptom relief from allergic rhinitis. Consideration of frequency, severity, and site of symptoms is important in directing pharmacotherapy efficacy and maximizing cost-effectiveness. The agents available include antihistamines, decongestants, steroids, mast cell stabilizers, anticholinergic agents, and mucolytics. Appropriate indications for each and combinations of various agents are discussed within the context of drug efficacy, side effects, affordability, and ease of compliance. The direct and indirect costs of allergic rhinitis are not well delineated but are explored to put the costs of therapy in perspective.
本文提供了药物治疗指南，以最大程度缓解过敏性鼻炎的症状。在指导药物治疗效果和实现成本效益最大化方面，考虑症状的频率、严重程度和部位非常重要。可用的药物包括抗组胺药、减充血剂、类固醇、肥大细胞稳定剂、抗胆碱能药物和黏液溶解剂。在药物疗效、副作用、可承受性和依从性的背景下，讨论了每种药物的适用指征以及各种药物的联合使用。过敏性鼻炎的直接和间接成本尚未明确界定，但会进行探讨以便正确看待治疗成本。
