[Anthropo-ecological aspects of occupational health and various biochemical approaches to the problem of its evaluation in workers in high risk occupations].

This paper presents the concept of occupational health of man, interpreted as the process of maintenance and development of regulatory properties of the body and his physical, psychic and social well-being, which provide high reliability of his professional activities, professional longevity and maximal lifetime. The paper discusses the main areas of biochemical investigations to evaluate occupational health of the flying personnel, which include identification of correlates between biochemical or immune changes and pathological or premorbid states, that reduce tolerance to environmental effects, as well as study of functional specificities related to the reserves and mechanisms of implementation of adaptive capabilities of the human body. It gives detailed biochemical data derived from pilots with neurotic problems and biochemical indicators of stress tolerance measured during exposure to +Gz acceleration, angular acceleration, hyperthermia, hypoxia, and exercise.