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在 CABG 手术前进行“预康复”可以改善身体机能和抑郁状况。

"Prehabilitation" prior to CABG surgery improves physical functioning and depression.

机构信息

British Heart Foundation Care & Education Research Group, Department of Health Sciences, University of York, York, UK.

出版信息

Int J Cardiol. 2009 Feb 6;132(1):51-8. doi: 10.1016/j.ijcard.2008.06.001. Epub 2008 Aug 15.

Abstract

BACKGROUND

Many patients demonstrate psychological distress and reduced physical activity before coronary artery bypass graft surgery (CABG). Here we evaluated the addition of a brief, cognitive-behavioural intervention (the HeartOp Programme) to routine nurse counselling for people waiting for CABG surgery.

METHODS

Randomised controlled trial comparing nurse counselling with the HeartOp programme to routine nurse counselling in 204 patients awaiting first time elective CABG. Primary outcome measures were: anxiety and length of hospital stay; secondary outcome measures were: depression, physical functioning, cardiac misconceptions and cost utility. Measures were collected prior to randomisation and after 8 weeks of their intervention prior to surgery, excepting length of hospital stay which was collected after discharge following surgery.

RESULTS

100 patients were randomised to intervention, 104 to control. At follow-up there were no differences in anxiety or length of hospital stay. There were significant differences in depression (difference=7.79, p=0.008, 95% CI=2.04-13.54), physical functioning (difference=0.82, p=0.001, 95%CI=0.34-1.3) and cardiac misconceptions (difference=2.56, p<0.001, 95%CI=1.64-3.48) in favour of the HeartOp Programme. The only difference to be maintained following surgery was in cardiac misconceptions. The HeartOp Programme was found to have an Incremental Cost Effectiveness Ratio (ICER) of pound 288.83 per Quality-Adjusted Life Year.

CONCLUSIONS

Nurse counselling with the HeartOp Programme reduces depression and cardiac misconceptions and improves physical functioning before bypass surgery significantly more than nurse counselling alone and meets the accepted criteria for cost efficacy.

摘要

背景

许多患者在冠状动脉旁路移植术(CABG)前表现出心理困扰和体力活动减少。在这里,我们评估了在等待 CABG 手术的患者中,将简短的认知行为干预(HeartOp 计划)添加到常规护士咨询中的效果。

方法

比较了 204 名等待首次选择性 CABG 的患者接受护士咨询与 HeartOp 计划的随机对照试验。主要结果指标为:焦虑和住院时间;次要结果指标为:抑郁、身体功能、心脏误解和成本效益。在随机分组前和手术前干预 8 周后收集了这些指标,除了在手术后出院后收集的住院时间。

结果

100 名患者被随机分配到干预组,104 名患者被分配到对照组。在随访时,焦虑或住院时间没有差异。抑郁(差异=7.79,p=0.008,95%CI=2.04-13.54)、身体功能(差异=0.82,p=0.001,95%CI=0.34-1.3)和心脏误解(差异=2.56,p<0.001,95%CI=1.64-3.48)方面有显著差异,对 HeartOp 计划有利。手术后唯一保持不变的是心脏误解。HeartOp 计划的增量成本效益比(ICER)为每质量调整生命年 288.83 英镑。

结论

与单独的护士咨询相比,护士咨询与 HeartOp 计划相结合可显著降低抑郁和心脏误解,改善旁路手术前的身体功能,且符合成本效益的接受标准。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c06/2643012/892920062219/gr1.jpg

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