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长期治疗的麻风病患者神经干中的分枝杆菌。

Mycobacteria in nerve trunks of long-term treated leprosy patients.

作者信息

Pereira J H, Palande D D, Gschmeissner S E

机构信息

Department of Anatomy, Royal College of Surgeons of England, East Grinstead.

出版信息

Lepr Rev. 1991 Jun;62(2):134-42. doi: 10.5935/0305-7518.19910015.

Abstract

Mycobacteria were present in 4 out of 8 mixed peripheral nerve trunks from patients (3 BT and 1 BL) treated with DDS and/or MDT for periods ranging from 21 months to 8 years. Most of the bacilli appeared to be 'whole'. Nerve destruction with areas of granulomatous infiltration appeared more active than expected. Possible reasons for a continued presence of bacilli in treated nerves and its implications in 'relapse' are discussed.

摘要

在接受氨苯砜和/或多药联合治疗21个月至8年的患者的8条混合性周围神经干中,有4条(3条结核样型和1条界线类)发现了分枝杆菌。大多数杆菌看起来是“完整的”。伴有肉芽肿浸润区域的神经破坏似乎比预期更活跃。文中讨论了治疗后神经中杆菌持续存在的可能原因及其对“复发”的影响。

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