Auler Jose Otavio C, Galas Filomena R B G, Sundin Marcia R, Hajjar Ludhmila A
Shock. 2008 Oct;30 Suppl 1:18-22. doi: 10.1097/SHK.0b013e3181818708.
In critically ill patients, it is important to predict which patients will have their systemic blood flow increased in response to volume expansion to avoid undesired hypovolemia and fluid overloading. Static parameters such as the central venous pressure, the pulmonary arterial occlusion pressure, and the left ventricular end-diastolic dimension cannot accurately discriminate between responders and nonresponders to a fluid challenge. In this regard, respiratory-induced changes in arterial pulse pressure have been demonstrated to accurately predict preload responsiveness in mechanically ventilated patients. Some experimental and clinical studies confirm the usefulness of arterial pulse pressure as a useful tool to guide fluid therapy in critically ill patients.
在危重症患者中，预测哪些患者会因容量扩充而使全身血流增加非常重要，以避免出现不期望的低血容量和液体超负荷。诸如中心静脉压、肺动脉闭塞压和左心室舒张末期内径等静态参数无法准确区分对液体挑战有反应者和无反应者。在这方面，已证明呼吸引起的动脉脉压变化可准确预测机械通气患者的前负荷反应性。一些实验和临床研究证实动脉脉压作为指导危重症患者液体治疗的有用工具是有效的。
