一种具有8-氮杂双环[3.2.1]辛烷骨架的新型受限脯氨酸类似物。
A new constrained proline analogue with an 8-azabicyclo[3.2.1]octane skeleton.
作者信息
Casabona Diego, Jiménez Ana I, Cativiela Carlos
机构信息
Departamento de Química Orgánica, Instituto de Ciencia de Materiales de Aragón, Universidad de Zaragoza-CSIC, 50009 Zaragoza, Spain.
出版信息
Tetrahedron. 2007 Jun 4;63(23):5056-5061. doi: 10.1016/j.tet.2007.03.115.
Abstract
A straightforward synthesis of 8-azabicyclo[3.2.1]octane-1-carboxylic acid, a new proline analogue with a bicyclic structure, is described. The procedure makes use of readily available starting materials and involves simple, high-yielding transformations.
摘要
本文描述了一种新型双环结构脯氨酸类似物8-氮杂双环[3.2.1]辛烷-1-羧酸的直接合成方法。该方法使用易于获得的起始原料，且涉及简单、高产率的转化反应。
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