Därr R, Ziller V, Hadji P, Hofbauer L C
Bereich Endokrinologie/Diabetes/Metabolische Knochenerkrankungen, Medizinische Klinik und Poliklinik III, Universitätsklinikum der Technischen Universität Dresden, Fetscherstrasse 74, 01307, Dresden, Deutschland.
Internist (Berl). 2008 Oct;49(10):1170, 1172-7. doi: 10.1007/s00108-008-2114-z.
Osteoporosis and osteomalacia are systemic metabolic bone diseases characterized by an impaired composition, architecture, and quality of bone. In light of the demographic development and the recent use of sensitive tests, both diseases are increasingly diagnosed. Subjects at high risk include elderly, chronically hospitalized patients, and nursing home residents. Patients with gastrointestinal, rheumatologic and endocrine disorders are also at risk for the development of osteoporosis or osteomalacia. In this review, we will discuss practical aspects of the clinical presentation and the diagnosis of osteoporosis and osteomalacia.
骨质疏松症和骨软化症是全身性代谢性骨病,其特征是骨的组成、结构和质量受损。鉴于人口结构的变化以及近期敏感检测方法的应用,这两种疾病的诊断越来越多。高危人群包括老年人、长期住院患者和养老院居民。患有胃肠道、风湿性和内分泌疾病的患者也有患骨质疏松症或骨软化症的风险。在本综述中,我们将讨论骨质疏松症和骨软化症临床表现及诊断的实际问题。