Memtsoudis Stavros G, González Della Valle Alejandro, Besculides Melanie C, Gaber Licia, Sculco Thomas P
Department of Anesthesiology, Hospital for Special Surgery, Weill Medical College of Cornell University, New York, NY 10021, USA.
Clin Orthop Relat Res. 2008 Nov;466(11):2617-27. doi: 10.1007/s11999-008-0402-5. Epub 2008 Aug 14.
Patients undergoing bilateral total knee arthroplasty (BTKA) may have higher complication rates and mortality than those undergoing a unilateral procedure (UTKA). To evaluate this hypothesis, we analyzed nationally representative data collected for the National Hospital Discharge Survey on discharges after BTKA, UTKA, and revision TKA (RTKA) between 1990 and 2004. The demographics, comorbidities, in-hospital stay, complications, and mortality of each procedure were compared. An estimate of 4,159,661 discharges (153,259 BTKAs; 3,672,247 UTKAs; 334,155 RTKAs) were included. Patients undergoing BTKA were younger (1.5 years) and had a lower prevalence of comorbidities for hypertension (versus UTKA), diabetes, pulmonary disease, and coronary artery disease (versus UTKA and RTKA). The length of hospitalization was 5.8 days for BTKA, 5.3 for UTKA, and 5.4 for RTKA. Despite similar length of hospitalization, the prevalence of procedure-related complications was higher for BTKA (12.2%) compared with UTKA (8.2%) and RTKA (8.7%). In-hospital mortality was highest for patients undergoing BTKA (BTKA, 0.5%; UTKA, 0.3%; RTKA, 0.3%). Patients undergoing BTKA had a 1.6 times higher rate of procedure-related complications and mortality compared with those undergoing UTKA. Outcomes for patients undergoing RTKA for most variables were similar to those for UTKA. BTKA, advanced age, and male gender were independent risk factors for complications and mortality after TKA.
Level III, therapeutic study. See the Guidelines for Authors for a complete description of levels of evidence.
接受双侧全膝关节置换术(BTKA)的患者可能比接受单侧手术(UTKA)的患者有更高的并发症发生率和死亡率。为了评估这一假设,我们分析了1990年至2004年间全国医院出院调查收集的关于BTKA、UTKA和翻修全膝关节置换术(RTKA)后出院情况的具有全国代表性的数据。比较了每种手术的人口统计学、合并症、住院时间、并发症和死亡率。纳入了估计4159661例出院病例(153259例BTKA;3672247例UTKA;334155例RTKA)。接受BTKA的患者更年轻(年轻1.5岁),高血压合并症的患病率低于UTKA,糖尿病、肺部疾病和冠状动脉疾病的患病率低于UTKA和RTKA。BTKA的住院时间为5.8天,UTKA为5.3天,RTKA为5.4天。尽管住院时间相似,但BTKA的手术相关并发症患病率(12.2%)高于UTKA(8.2%)和RTKA(8.7%)。接受BTKA的患者住院死亡率最高(BTKA为0.5%;UTKA为0.3%;RTKA为0.3%)。与接受UTKA的患者相比,接受BTKA的患者手术相关并发症和死亡率高1.6倍。大多数变量下接受RTKA的患者的结果与接受UTKA的患者相似。BTKA、高龄和男性是全膝关节置换术后并发症和死亡率的独立危险因素。
III级治疗性研究。有关证据水平的完整描述,请参阅作者指南。