[胃黏膜下癌的DNA倍体及其与淋巴结转移的关系]
[DNA ploidy in submucosal cancer of the stomach and its relationship to lymph node metastasis].
作者信息
Hashizume T, Yamaura T, Fukuda T, Sugihara S, Nakajima T, Nagamachi Y
机构信息
Department of Surgery, Gunma Cancer Center Hospital, Maebashi, Japan.
出版信息
Nihon Geka Gakkai Zasshi. 1991 Apr;92(4):397-400.
The relationship between DNA ploidy and lymph node metastasis was determined in 40 cases of gastric cancer confined to the submucosa (with lymph node metastasis 20 cases and without 20 cases). The DNA ploidy patterns were classified as follows: Type D, Type A1 and Type A2. Of the 20 cases with lymph node metastasis, 1 was Type D, 7 were Type A1 and 12 were Type A2. The likelihood of lymph node metastasis was 12.5% (1/8) for Type D, 43.8% (7/16) for Type A1 and 75.0% (12/16) for Type A2. It is concluded that although gastric cancer confined to the submucosa is classified as early one, analysis of DNA content places such tumors with lymph node metastasis into the advanced cancer category.
对40例局限于黏膜下层的胃癌（其中有淋巴结转移20例，无淋巴结转移20例）进行了DNA倍体与淋巴结转移关系的研究。DNA倍体模式分类如下：D型、A1型和A2型。在20例有淋巴结转移的病例中，1例为D型，7例为A1型，12例为A2型。D型淋巴结转移的可能性为12.5%（1/8），A1型为43.8%（7/16），A2型为75.0%（12/16）。结论是，尽管局限于黏膜下层的胃癌被归类为早期胃癌，但对DNA含量的分析表明，此类有淋巴结转移的肿瘤应归为进展期癌。
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