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男性包皮环切术能降低英国的艾滋病病毒感染率吗?

Could male circumcision reduce HIV incidence in the UK?

作者信息

Rice B D, Delpech V C, Evans B G

机构信息

Department of HIV and STIs, Health Protection Agency Centre for Infections, Colindale, London, UK.

出版信息

HIV Med. 2008 Jul;9(6):329-31. doi: 10.1111/j.1468-1293.2008.00547.x.

Abstract

We consider the public health relevance of three recent African clinical trials showing male circumcision (MC) to reduce female-to-male transmission of HIV for the UK. Although heterosexually acquired HIV infections now account for the majority of new diagnoses in the UK each year, it is important to note that when considering the public health relevance of MC for the UK a large majority of these infections are acquired abroad. Men who have sex with men (MSM) remain those most at risk of acquiring their HIV infection in the UK. The efficacy and effectiveness of MC among MSM and in particular its protective role in unprotected anal intercourse between men remains unknown. Any future consideration of the role of MC in reducing HIV incidence in the UK should not be at the expense of weakening existing effective interventions.

摘要

我们考量了近期三项非洲临床试验的公共卫生意义,这些试验表明男性包皮环切术(MC)可减少英国境内女性向男性传播艾滋病毒的情况。尽管目前每年在英国新诊断出的艾滋病毒感染病例中,异性传播感染占大多数,但需要注意的是,在考量男性包皮环切术对英国的公共卫生意义时,这些感染中的绝大多数是在国外感染的。男男性行为者(MSM)仍是英国感染艾滋病毒风险最高的人群。男性包皮环切术在男男性行为者中的疗效和有效性,尤其是其在男性间无保护肛交中的保护作用仍不明确。未来任何关于男性包皮环切术在降低英国艾滋病毒发病率方面作用的考量,都不应以削弱现有有效干预措施为代价。

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