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[Surgical treatment of extraperitoneal rectal cancer].

作者信息

Pappalardo Giuseppe, Spoletini Domenico, Proposito Delia, Conte Anna Maria, Giorgiano Fabio, Nunziale Aldo, Frattaroli Fabrizio Maria

机构信息

Dipartimento P. Stefanini, I Facoltà di Medicina e Chirurgia Università La Sapienza Roma, Azienda Policlinico Umberto I.

出版信息

Chir Ital. 2008 May-Jun;60(3):337-44.

PMID:18709771
Abstract

The aim of the study was to evaluate the results of open surgery with sphincter preservation and nerve-sparing total mesorectal excision and a fast-track protocol, without a protective stoma in a consecutive series of patients with extraperitoneal rectal cancer. From 1998 to 2007, 89 patients with extraperitoneal rectal cancer were treated according to a prospective protocol. Eight-six patients were submitted to anterior resection with a low or ultra-low anastomosis and nerve-sparing total mesorectal excision. Fifty-four patients received neoadjuvant therapy. Twenty-eight patients were treated according to a fast-track postoperative protocol. Primary protective colostomies were performed in 6 cases (6.9%), while a secondary colostomy was necessary in 3 patients (3.4%). There was just one postoperative death (1.1%) and major morbidity occurred in 12.3%. Seven patients developed anastomotic dehiscence; 3 were successfully treated with a secondary colostomy and 4 were treated conservatively. 68.4% of the patients treated with the fast-track protocol could be discharged on postoperative day 4. 73% of patients were still surviving at a 5-year follow-up (48 patients). The incidence of local recurrences was 3.1%. Anterior resection in the form of open nerve-sparing total mesorectal excision with selective use of neoadjuvant therapy can be successfully performed without a protective stoma in more than 80% of patients. The fast-track protocol seems to increase the quality of the patient's postoperative condition and reduce the hospital stay.

摘要

相似文献

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[Surgical treatment of extraperitoneal rectal cancer].
Chir Ital. 2008 May-Jun;60(3):337-44.
2
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G Chir. 2014 Nov-Dec;35(11-12):293-301.