Tordzhian I Kh
Antibiotiki. 1976 Sep;21(9):775-9.
The effect of subinhibitory concentrations of monomycin on the submicroscopic structures of 2 strains of S. typhi, 5 and 799 was studied. It was shown that formation of filamentoue forms, separation of the cell wall, thinning out of the cytoplasm granular component, increasing of the size of the matter with low electron optic density of fine granular structure were common in the cell response of both strains. Formation of vacuoli containing the thinned out granular component, filterable elements and complex membrane structures followed by their liberation into the medium and formation of the forms devoid of the cell walls was a characteristic peculiar property of the cell response in strain 799. The cells of strain 5 were characterized by formation of large granular osmiefilic matters and their excretion from the cells.
研究了亚抑制浓度的莫诺霉素对两株伤寒沙门氏菌5型和799型亚微观结构的影响。结果表明，两株菌的细胞反应中常见丝状形态的形成、细胞壁分离、细胞质颗粒成分变薄、低电子光学密度的细颗粒结构物质大小增加。含有变薄的颗粒成分、可过滤成分和复杂膜结构的液泡形成，随后它们释放到培养基中并形成无细胞壁的形态，这是799型菌株细胞反应的一个特征特性。5型菌株的细胞特征是形成大的颗粒状嗜锇物质并从细胞中排出。
