Seidel H, Fürll M, Fürll B
Arch Exp Veterinarmed. 1976;30(4):481-90.
No marked gluconeogenetic performance was recordable from nursed piglets aged, between one and five days, in response to ACTH nor glucocorticosteroid application. Store pigs, aged twelve weeks, however, exhibited glucose rises of 34 per cent one hour after injection or 55 per cent three hours from ACTH application. The point was made, in an attempt to elucidate the above findings, that in newborn piglets, few days after birth, the gluconeogenetic capacity is insufficient because of functional immaturity of the liver. The behaviours of several metabolites in the liver and muscles of store pigs were examined under differentiated model conditions to check up and verify that view.
在1至5日龄的哺乳仔猪中,无论使用促肾上腺皮质激素(ACTH)还是糖皮质激素,均未记录到明显的糖异生表现。然而,12周龄的育肥猪在注射ACTH后1小时血糖升高34%,3小时后升高55%。为了阐明上述发现,有人指出,新生仔猪出生后几天内,由于肝脏功能不成熟,糖异生能力不足。在不同的模型条件下,对育肥猪肝脏和肌肉中几种代谢物的行为进行了检查,以核实这一观点。