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人二倍体细胞培养物中干扰素的产生。

Production of interferon in human diploid cell cultures.

作者信息

Zielińska-Jenczylik J, Rzucidlo Z, Sypula A, Blach-Olszewska Z, Kidankiewicz T

出版信息

Arch Immunol Ther Exp (Warsz). 1976;24(5):769-75.

PMID:187142
Abstract

Eleven human diploid cell lines were compared for their ability to produce interferon in response to Newcastle Disease Virus. Sensitivity of the cultures of MM, Sindbis VSV and VR viruses was also studied. Human cells derived from various tissue of a single embryo responded variably to interferon inducer. Using selected viruses interferon production was studied in two systems, in cultures of leukocytes and in human embryonic cells.

摘要

对11种人二倍体细胞系产生干扰素以应对新城疫病毒的能力进行了比较。还研究了MM、辛德毕斯病毒、水泡性口炎病毒(VSV)和VR病毒培养物的敏感性。源自单个胚胎不同组织的人类细胞对干扰素诱导剂的反应各不相同。使用选定的病毒,在白细胞培养物和人类胚胎细胞这两个系统中研究了干扰素的产生。

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