Ashri Nahed Y
Department of Preventive Dental Science, Division of Periodontics, College of Dentistry, King Saud University, P.O. Box 60169, Riyadh 11545, Saudi Arabia.
J Int Acad Periodontol. 2008 Jul;10(3):81-6.
Various approaches for treating the periodontal condition associated with Papillon-Lefèvre syndrome (PLS) have been reported. These include oral hygiene instruction, use of mouth rinses, frequent debridement, multiple antibiotic regimens, periodontal surgery, extraction of hopeless teeth, and extraction of all primary teeth. The objective of this paper is to review the literature on the different treatment approaches of patients with PLS and to illustrate the importance of early diagnosis as well as treatment in long-term maintenance of oral health. Because PLS is rare, most publications are case reports, and very few document long-term successful treatment of the periodontal condition. Several treatment approaches are summarized in this paper with the long-term reports. The importance of early diagnosis is highlighted. The recommendation is that young patients with skin lesions and severe periodontal destruction together with premature loss of teeth should be referred to a periodontist as early as possible. This should prevent or delay tooth loss and enhance early replacement of missing teeth for preservation of function and esthetics. In conclusion, successful periodontal management of PLS patients remains challenging. However, as our understanding of the etiological factors increases, it is hoped that successful treatment strategies will be developed.
已有报道称有多种方法可用于治疗与帕皮永-勒费弗尔综合征（PLS）相关的牙周疾病。这些方法包括口腔卫生指导、使用漱口水、频繁清创、多种抗生素治疗方案、牙周手术、拔除无保留价值的牙齿以及拔除所有乳牙。本文的目的是回顾关于PLS患者不同治疗方法的文献，并阐明早期诊断以及治疗在长期维持口腔健康方面的重要性。由于PLS较为罕见，大多数出版物都是病例报告，很少有文献记录牙周疾病的长期成功治疗情况。本文结合长期报告总结了几种治疗方法。强调了早期诊断的重要性。建议将有皮肤病变、严重牙周破坏以及牙齿过早缺失同时出现的年轻患者尽早转诊给牙周病专家。这应能预防或延缓牙齿缺失，并促进尽早修复缺失牙齿以保留功能和美观。总之，成功管理PLS患者的牙周疾病仍然具有挑战性。然而，随着我们对病因因素的认识不断增加，希望能够制定出成功的治疗策略。
