Stanley N F
Aust Fam Physician. 1976 Jul;5(6):823-30.
The role of viruses as causative agents of cancer in man has been examined for more than 50 years. These studies have recently been intensified by employing newly developed, more sensitive techniques in virology and immunology. In spite of proof that viruses cause cancer in animals and that about one-quarter of the known 600 viruses possess oncogenic potential, definite proof of their aetiology in human cancer remains elusive even though cancer research is a highly respectable and costly pursuit. Nevertheless, the probabilities are high that human cancer viruses have been and will be identified and that their induced diseases can be prevented or controlled. It is accepted that some benign tumours of man (such as warts) are induced by a virus infection. This article examines the current situation and highlights the difficulties, hopes and usefulness of research in this field.
病毒作为人类癌症致病因子的作用已被研究了50多年。最近,通过运用病毒学和免疫学新开发的、更灵敏的技术,这些研究得到了加强。尽管有证据表明病毒可在动物体内引发癌症,而且已知的600种病毒中约有四分之一具有致癌潜力,但即便癌症研究是一项备受尊崇且耗资巨大的事业,病毒在人类癌症病因学方面的确凿证据仍难以捉摸。然而,人类癌症病毒已被识别以及将来会被识别的可能性很大,而且由它们引发的疾病能够被预防或控制。人们公认,人类的一些良性肿瘤(如疣)是由病毒感染诱发的。本文探讨了当前的形势,并着重介绍了该领域研究的困难、希望和实用性。