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冠状动脉搭桥手术住院患者术前和术后心肺康复:一项随机对照试验。

Pre- and postoperative cardiopulmonary rehabilitation in hospitalized patients undergoing coronary artery bypass surgery: a randomized controlled trial.

作者信息

Herdy Artur H, Marcchi Patrícia L B, Vila Adriano, Tavares Claudia, Collaço Jauro, Niebauer Josef, Ribeiro Jorge P

机构信息

Santa Catarina Heart Institute, Florianópolis, Brazil.

出版信息

Am J Phys Med Rehabil. 2008 Sep;87(9):714-9. doi: 10.1097/PHM.0b013e3181839152.

DOI:10.1097/PHM.0b013e3181839152
PMID:18716482
Abstract

OBJECTIVE

Patients who have to wait in the hospital for coronary artery bypass surgery (CABG) are exposed to the potential risks of immobilization. This clinical trial was conducted to evaluate the effects of an in-hospital cardiopulmonary rehabilitation program performed before and after CABG on postoperative outcomes.

DESIGN

Fifty-six patients who had to wait for CABG in-hospital were randomly assigned to a cardiopulmonary rehabilitation (Rehab; n = 29) or to usual care (Control; n = 27). In the Rehab group, intervention lasted for at least 5 days preoperatively until discharge. The program consisted of phase I cardiac rehabilitation associated with respiratory physical therapy. Outcomes were blindly evaluated.

RESULTS

By hospital discharge, Rehab patients presented a shorter time to endotracheal extubation (1054 +/- 376 vs. 1340 +/- 666 min, P = 0.05), a reduction in the incidence of pleural effusion (relative risk [RR] = 0.2; 95% confidence interval [CI]: 0.5-0.8), atelectasis (RR = 0.15; 95% CI: 0.03-0.8), pneumonia (0 vs. 7 cases, [P = 0.004]), and atrial fibrillation or flutter (RR = 0.2; 95% CI: 0.05-0.8). Length of in-hospital stay after surgery was also reduced in the Rehab group (5.9 +/- 1.1 vs. 10.3 +/- 4.6 days [P < 0.001]).

CONCLUSION

Pre- and postoperative cardiopulmonary rehabilitation in patients who await CABG in the hospital is superior to standard care and leads to a reduced rate of postoperative complications and shorter hospital stay.

摘要

目的

必须在医院等待冠状动脉搭桥手术(CABG)的患者面临着制动带来的潜在风险。本临床试验旨在评估CABG前后进行的院内心肺康复计划对术后结局的影响。

设计

56例必须在院内等待CABG的患者被随机分为心肺康复组(康复组;n = 29)或常规护理组(对照组;n = 27)。在康复组中,干预持续至术前至少5天直至出院。该计划包括与呼吸物理治疗相关的I期心脏康复。结局采用盲法评估。

结果

出院时,康复组患者气管插管拔除时间更短(1054±376 vs. 1340±666分钟,P = 0.05),胸腔积液发生率降低(相对风险[RR] = 0.2;95%置信区间[CI]:0.5 - 0.8),肺不张(RR = 0.15;95% CI:0.03 - 0.8),肺炎(0例 vs. 7例,[P = 0.004]),以及心房颤动或扑动(RR = 0.2;95% CI:0.05 - 0.8)。康复组术后住院时间也缩短(5.9±1.1天 vs. 10.3±4.6天[P < 0.001])。

结论

在医院等待CABG的患者进行术前和术后心肺康复优于标准护理,可降低术后并发症发生率并缩短住院时间。

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