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自膨式金属支架在梗阻性结直肠癌姑息治疗中的应用——谨防穿孔!

Adoption of self-expanding metallic stents in the palliative treatment of obstructive colorectal cancer-look out for perforations!

作者信息

Varpe Pirita, Huhtinen Heikki, Rantala Arto, Salminen Paulina, Sarparanta Heikki, Grönroos Juha

机构信息

Department of Surgery, Turku University Central Hospital, Turku, Finland.

出版信息

Surg Laparosc Endosc Percutan Tech. 2008 Aug;18(4):353-6. doi: 10.1097/SLE.0b013e3181761fb8.

Abstract

Self-expanding metallic stents (SEMSs) are increasingly used for the palliative treatment of inoperable colorectal cancer. The aim of the current study was to analyze the safety and efficacy of SEMS in the palliative treatment of obstructive colorectal cancer. Between 2003 and 2006, SEMS placement was attempted in 26 patients suffering from inoperable obstructive colorectal cancer. The recovery of the patients and the outcome of this treatment modality were analyzed prospectively. SEMS was successfully inserted in 19 (73%) of 26 patients. In 16 (84%) of these 19 cases, the placement of SEMS was the definitive treatment of colorectal obstruction and no additional surgical palliation was needed. There were 3 (16%) colonic perforations related to stent application. SEMS insertion seems to be an effective alternative in the palliative treatment of patients with malignant colorectal obstruction. However, perforation is a dangerous complication of the procedure.

摘要

自膨式金属支架(SEMSs)越来越多地用于无法手术切除的结直肠癌的姑息治疗。本研究的目的是分析SEMS在梗阻性结直肠癌姑息治疗中的安全性和有效性。2003年至2006年期间,对26例无法手术的梗阻性结直肠癌患者尝试进行SEMS置入。对患者的恢复情况及这种治疗方式的结果进行了前瞻性分析。26例患者中有19例(73%)成功插入SEMS。在这19例中的16例(84%)中,SEMS置入是结直肠梗阻的确定性治疗方法,无需额外的手术姑息治疗。有3例(16%)结肠穿孔与支架应用有关。SEMS置入似乎是恶性结直肠梗阻患者姑息治疗的一种有效替代方法。然而,穿孔是该手术的一种危险并发症。

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