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青少年精索静脉曲张修复术中使用鱼肝油酸钠硬化疗法的结果及并发症

Results and complications of adolescent varicocele repair with intraoperative sodium morrhuate sclerotherapy.

作者信息

Lebed Brett, Packer Michael, Husmann Douglas, Zaontz Mark

机构信息

Department of Urology, Temple University Children's Hospital, Philadelphia, Pennsylvania, USA.

出版信息

J Urol. 2008 Oct;180(4 Suppl):1837-41. doi: 10.1016/j.juro.2008.04.072. Epub 2008 Aug 21.

Abstract

PURPOSE

Adolescent varicocele has been shown to affect spermatogenesis and correlate with decreased ipsilateral testicular volume, prompting treatment in a select population. We report our experience with 3 varicocele ligation procedures in concordance with sclerotherapy in adolescent patients.

MATERIALS AND METHODS

A total of 120 males underwent varicocele surgery at our institutions during an 8-year period. Sodium morrhuate sclerotherapy was used in 91 patients and 73 adolescent males fulfilled the 6-month followup criteria. The 73 males who were 9 to 17 years old underwent a total of 75 (bilateral in 2) procedures for varicocele treatment. Of the patients 23 underwent subinguinal microscopic varicocelectomy (group 1), 9 underwent loupe assisted subinguinal varicocelectomy (group 2) and 41 underwent loupe assisted inguinal varicocelectomy (group 3). All patients received intraoperative sclerotherapy using sodium morrhuate injection. Outcome measures included recurrence, complications and catch-up growth at a minimum of 6 months of followup.

RESULTS

The varicocele recurrence rate was 2.7% in patients receiving combined surgical ligation and sclerotherapy ablation. Group 1 had 2 recurrent varicoceles and no hydrocele formation, group 2 had no varicocele recurrence and no hydrocele formation, and group 3 had no varicocele recurrence and 2 postoperative hydroceles. Catch-up growth in the ipsilateral testis was seen in 85% of patients. No atrophy or testicular loss was noted.

CONCLUSIONS

This preliminary experience with combined surgical ligation and sclerotherapy ablation in the adolescent population resulted in low varicocele recurrence with minimal morbidity. Outcomes of loupe assisted varicocelectomy appear to be improved compared to those in previous studies, alluding to an advantage in the addition of sclerotherapy.

摘要

目的

青少年精索静脉曲张已被证实会影响精子发生,并与同侧睾丸体积减小相关,这促使在特定人群中进行治疗。我们报告了在青少年患者中联合硬化疗法进行3种精索静脉曲张结扎手术的经验。

材料与方法

在8年期间,共有120名男性在我们机构接受了精索静脉曲张手术。91例患者采用鱼肝油酸钠硬化疗法,73例青少年男性符合6个月随访标准。这73名年龄在9至17岁的男性共接受了75次(2例为双侧)精索静脉曲张治疗手术。其中,23例患者接受了腹股沟下显微镜下精索静脉结扎术(第1组),9例接受了放大镜辅助腹股沟下精索静脉结扎术(第2组),41例接受了放大镜辅助腹股沟精索静脉结扎术(第3组)。所有患者术中均采用鱼肝油酸钠注射进行硬化治疗。观察指标包括复发、并发症以及至少6个月随访期的追赶生长情况。

结果

接受联合手术结扎和硬化疗法消融的患者中,精索静脉曲张复发率为2.7%。第1组有2例精索静脉曲张复发,无鞘膜积液形成;第2组无精索静脉曲张复发,无鞘膜积液形成;第3组无精索静脉曲张复发,有2例术后鞘膜积液。85%的患者同侧睾丸出现追赶生长。未发现萎缩或睾丸丢失情况。

结论

青少年人群联合手术结扎和硬化疗法消融的初步经验导致精索静脉曲张复发率低,发病率最小。与先前研究相比,放大镜辅助精索静脉结扎术的结果似乎有所改善,这表明添加硬化疗法具有优势。

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