一个与SLITRK1基因无关的患有抽动秽语综合征的意大利家庭中强迫症的精神病理学特征。
Psychopathological features of obsessive-compulsive disorder in an Italian family with Gilles de la Tourette syndrome not linked to the SLITRK1 gene.
作者信息
Pasquini Massimo, Fabbrini Giovanni, Berardelli Isabella, Bonifati Vincenzo, Biondi Massimo, Berardelli Alfredo
机构信息
Department of Psychiatric Science and Psychological Medicine, Sapienza University of Rome, Rome, Italy.
出版信息
Psychiatry Res. 2008 Oct 30;161(1):109-11. doi: 10.1016/j.psychres.2008.02.012. Epub 2008 Aug 21.
We report the psychopathological features in a large Italian family with Gilles de la Tourette syndrome not linked to the SLITRK1 gene. Of the 23 living family members, 14 were evaluated using the Structured Clinical Interview for DSM-IV, the Yale-Brown Obsessive-Compulsive Scale, the Clinical Global Impression and the Global Assessment of Functioning scale. Ten patients were found to have obsessive-compulsive disorder in which tic-like compulsions predominated. The distinctive feature of this family is the high frequency of obsessive-compulsive disorder with various clinical phenotypes.
我们报告了一个与SLITRK1基因无关的患有抽动秽语综合征的意大利大家庭的精神病理学特征。在23名在世的家庭成员中，14人使用《精神疾病诊断与统计手册》第四版的结构化临床访谈、耶鲁-布朗强迫量表、临床总体印象量表和功能总体评估量表进行了评估。发现10名患者患有强迫症，其中抽动样强迫行为占主导。这个家庭的独特之处在于具有各种临床表型的强迫症的高发病率。
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