Stornetta R L
Department of Pharmacology, University of Virginia Health System, P.O. Box 800735, 1300 Jefferson Park Avenue, Charlottesville, VA 22908, USA.
Respir Physiol Neurobiol. 2008 Dec 10;164(1-2):18-27. doi: 10.1016/j.resp.2008.07.024.
Identifying the major ionotropic neurotransmitter in a respiratory neuron is of critical importance in determining how the neuron fits into the respiratory system, whether in producing or modifying respiratory drive and rhythm. There are now several groups of respiratory neurons whose major neurotransmitters have been identified and in some of these cases, more than one transmitter has been identified in particular neurons. This review will describe the physiologically identified neurons in major respiratory areas that have been phenotyped for major ionotropic transmitters as well as those where more than one transmitter has been identified. Although the purpose of the additional transmitter has not been elucidated for any of the respiratory neurons, some examples from other systems will be discussed.
确定呼吸神经元中的主要离子型神经递质对于确定该神经元如何融入呼吸系统至关重要，无论是在产生还是调节呼吸驱动和节律方面。现在有几组呼吸神经元，其主要神经递质已被确定，在某些情况下，特定神经元中已鉴定出不止一种递质。本综述将描述主要呼吸区域中已针对主要离子型递质进行表型分析的生理上已确定的神经元，以及已鉴定出不止一种递质的神经元。尽管尚未阐明任何呼吸神经元中额外递质的作用，但将讨论其他系统中的一些例子。
