Headache Center of Atlanta Atlanta, GA, USA.
Neuropsychiatr Dis Treat. 2008 Feb;4(1):49-54. doi: 10.2147/ndt.s1871.
Triptans are recommended for the acute treatment of moderate to severe migraine or failure to respond to other acute migraine treatments. Seven triptans are available providing a wide range of choices. These triptans are more similar than dissimilar but patients do note differences in effectiveness and in tolerance. Also migraine situations may differ from attack to attack, providing the opportunity to exploit the uniqueness of a particular triptan. Frovatriptan has a uniquely long-half life, five times that of other triptans. This provides the opportunity to use frovatriptan in mini-prophylaxis such as in menstrual-related migraine and other situations, as well as use in long-lasting or recurrent migraine.
曲普坦类药物被推荐用于中重度偏头痛的急性治疗,或用于其他急性偏头痛治疗无效的情况。目前有七种曲普坦类药物可供选择,为患者提供了广泛的选择。这些曲普坦类药物在疗效和耐受性方面虽有差异,但更为相似。此外,偏头痛的发作情况可能会因发作而异,这为利用特定曲普坦类药物的独特性提供了机会。夫罗曲坦的半衰期特别长,是其他曲普坦类药物的五倍。这使得夫罗曲坦不仅可以用于迷你预防,如月经相关偏头痛和其他情况,还可以用于持续时间长或反复发作的偏头痛。