Xu Y J, Zhang Z X, Duan S F
Hospital of Tongji Medical University.
Zhonghua Nei Ke Za Zhi. 1991 Mar;30(3):138-40, 187.
In order to investigate pulmonary artery compliance (Cpa) and its relation with the clinical conditions and the other parameters of pulmonary hemodynamics in patients with chronic obstructive pulmonary disease (COPD), we performed right heart Swan-Ganz catheterization in 146 COPD patients and measured their Cpa with Engelberg's method. The results showed that Cpa of BB type patients was lower than that of PP type ones; patients with pulmonary hypertension or cor pulmonale had lower Cpa than those without. These results suggest that Cpa in COPD patients decreases as their clinical condition worsens. Cpa had close relation with other pulmonary hemodynamic parameters. It had significant negative correlation with pulmonary arterial mean pressure, pulmonary vascular resistance and right ventricular stroke work index and significant positive correlation with cardiac index and stroke volume index. Using Engelberg's method as the standard, we also compared Reuben's, Wang's and Zhong's methods which are all simpler than Engelberg's method for measuring Cpa clinically. The results showed that Cpa measured with Wang's method was the closest to that measured with Engelberg's method.
为了研究慢性阻塞性肺疾病（COPD）患者的肺动脉顺应性（Cpa）及其与临床状况和其他肺血流动力学参数的关系，我们对146例COPD患者进行了右心Swan-Ganz导管插入术，并采用恩格尔伯格法测量其Cpa。结果显示，BB型患者的Cpa低于PP型患者；患有肺动脉高压或肺心病的患者Cpa低于未患患者。这些结果表明，COPD患者的Cpa随着临床状况恶化而降低。Cpa与其他肺血流动力学参数密切相关。它与肺动脉平均压、肺血管阻力和右心室每搏功指数呈显著负相关，与心脏指数和每搏量指数呈显著正相关。以恩格尔伯格法为标准，我们还比较了鲁本法、王法和钟法，这三种方法在临床上测量Cpa都比恩格尔伯格法更简单。结果显示，用王法测量的Cpa最接近用恩格尔伯格法测量的结果。
