Swaim S F, Riddell K P, Geiger D L, Hathcock T L, McGuire J A
Scott-Ritchey Research Program for Research on Diseases of Small Pet Animals, College of Veterinary Medicine, Auburn University, AL 36849.
J Am Vet Med Assoc. 1991 Jun 1;198(11):1941-5.
The purpose of the prospective study reported here was to evaluate surgical preparation of canine paws. Three combinations of surgical scrub solutions and antiseptic solutions were used: (1) 7.5% povidone-iodine scrub/10% povidone-iodine solution; (2) 2% chlorhexidine acetate scrub/2% chlorhexidine diacetate solution; and (3) tincture of green soap/70% isopropyl alcohol. The control was warm (38 to 42 C) tap water. Four microbial colony counts were used to evaluate surgical preparation of 4 paws of 8 dogs. Specimens were obtained from the paws for a baseline microbial flora count. After surgical scrub was performed, additional specimens were obtained for bacteriologic culturing. Antiseptic was applied followed by collection of another specimen for bacteriologic culturing. A final specimen was obtained following a 24-hour period under a sterile occlusive bandage. The 3 scrub solutions and the tap water control resulted in lower colony counts following scrubbing of the paws; however, only the 3 antiseptic solutions resulted in further colony count reduction after their application. Evaluation of residual colony counts isolated from specimens taken after a 24-hour period under a sterile occlusive bandage revealed chlorhexidine and povidone-iodine scrub/antiseptic combinations to be similar in antibacterial activity, with significantly (P less than or equal to 0.05) lower colony counts than those from specimens of paws treated with either the tincture of green soap/isopropyl alcohol combination or the tap water control. The lack of a significant difference between the bacterial counts immediately after surgical preparation with povidone-iodine and chlorhexidine and their respective 24-hour residual counts, indicated no particular advantage to surgical preparation and occlusive bandaging 24 hours prior to surgery.(ABSTRACT TRUNCATED AT 250 WORDS)
本文报道的前瞻性研究旨在评估犬爪的手术准备情况。使用了三种手术擦洗溶液和抗菌溶液的组合:(1)7.5%聚维酮碘擦洗剂/10%聚维酮碘溶液;(2)2%醋酸氯己定擦洗剂/2%二醋酸氯己定溶液;(3)绿皂酊/70%异丙醇。对照组为温(38至42摄氏度)自来水。采用四种微生物菌落计数法评估8只狗的4只爪子的手术准备情况。从爪子获取标本进行基线微生物菌群计数。进行手术擦洗后,获取额外标本进行细菌培养。涂抹抗菌剂后,再采集另一份标本进行细菌培养。在无菌封闭绷带包扎24小时后获取最终标本。三种擦洗溶液和自来水对照组在爪子擦洗后菌落计数降低;然而,只有三种抗菌溶液在涂抹后导致菌落计数进一步降低。对在无菌封闭绷带包扎24小时后采集的标本中分离出的残留菌落计数进行评估发现,氯己定和聚维酮碘擦洗/抗菌组合的抗菌活性相似,其菌落计数显著(P小于或等于0.05)低于用绿皂酊/异丙醇组合或自来水对照组处理的爪子标本的菌落计数。手术准备后立即使用聚维酮碘和氯己定及其各自24小时残留计数之间没有显著差异,表明在手术前24小时进行手术准备和封闭绷带包扎没有特别优势。(摘要截短至250字)