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Spongipyran Synthetic Studies. Evolution of a Scalable Total Synthesis of (+)-Spongistatin 1.
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Asymmetric total synthesis of spongistatins 1 and 2.
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The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: the southern hemisphere EF segment.
Org Biomol Chem. 2005 Jul 7;3(13):2420-30. doi: 10.1039/b504149j. Epub 2005 May 24.
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Exploiting pseudo C2-symmetry for an efficient synthesis of the F-ring of the spongistatins.
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The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: the AB-spiroacetal segment.
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Evolution of Anion Relay Chemistry: Construction of Architecturally Complex Natural Products.
Acc Chem Res. 2020 Apr 21;53(4):988-1000. doi: 10.1021/acs.accounts.0c00076. Epub 2020 Apr 9.
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Design and Synthesis of Anti-Cancer Chimera Molecules Based on Marine Natural Products.
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Advances in exploring the therapeutic potential of marine natural products.
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An Enantioselective Cross-Dehydrogenative Coupling Catalysis Approach to Substituted Tetrahydropyrans.
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Synthesis of the phorboxazoles-potent, architecturally novel marine natural products.
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Organic synthesis in the Smith Group: a personal selection of a dozen lessons learned at the University of Pennsylvania.
J Antibiot (Tokyo). 2016 Apr;69(4):192-202. doi: 10.1038/ja.2016.21. Epub 2016 Mar 2.
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Conformation-activity relationships of polyketide natural products.
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Characterization of apoptosis induced by marine natural products in non small cell lung cancer A549 cells.
Cell Mol Life Sci. 2006 Oct;63(19-20):2377-86. doi: 10.1007/s00018-006-6264-7.
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In vitro and in vivo antifungal activities of the marine sponge constituent spongistatin.
Med Mycol. 2005 Aug;43(5):453-63. doi: 10.1080/13693780500050598.
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Total synthesis of spongistatin 1: a synthetic strategy exploiting its latent pseudo-symmetry.
Angew Chem Int Ed Engl. 2005 Aug 26;44(34):5433-8. doi: 10.1002/anie.200502008.
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Two-step synthesis of carbohydrates by selective aldol reactions.
Science. 2004 Sep 17;305(5691):1752-5. doi: 10.1126/science.1101710. Epub 2004 Aug 12.

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