Chiu S W, Ho S C, Hung Y C, Lee Y H
Department of Obstetrics, Gynecology Veterans General Hospital, Taichung, Taiwan, Republic of China.
Gaoxiong Yi Xue Ke Xue Za Zhi. 1991 Aug;7(8):429-34.
Clinicians are urgently searching for ways of differentiating a malignant from a benign ovarian mass. How to approach or what is the prognosis? Some have shown the CA-125 test combined with ultrasonography to be highly sensitive and specific, when compared to single parameter. We examined 238 patients who underwent laparotomy for adnexal mass. Of these 44 were found to suffer from malignant tumors and 194 from benign lesions. Before the operation, CA-125 level was measured; pelvic ultrasonography was performed on each patient and the sonographic data were evaluated on an echostructural scoring system. After a sophisticated computer assisted analysis, the results of the combined tests were CA-125 greater than or equal to 65 U/ml or US score greater than or equal to 8 with a sensitivity of 77.3%, a specificity of 81.4% and a diagnostic accuracy of 80.7%. Therefore we confirm that CA-125 may be considered as a useful adjunct to sonography in the differential diagnosis of adnexal mass.
临床医生迫切需要寻找区分卵巢恶性肿块和良性肿块的方法。如何处理以及预后如何？与单一参数相比，一些研究表明CA - 125检测联合超声检查具有高度的敏感性和特异性。我们检查了238例行附件肿块剖腹手术的患者。其中44例被发现患有恶性肿瘤，194例患有良性病变。术前测量CA - 125水平；对每位患者进行盆腔超声检查，并根据回声结构评分系统评估超声数据。经过复杂的计算机辅助分析，联合检测结果为CA - 125大于或等于65 U/ml或超声评分大于或等于8，敏感性为77.3%，特异性为81.4%，诊断准确性为80.7%。因此，我们证实CA - 125可被视为超声检查在附件肿块鉴别诊断中的有用辅助手段。
