Kawai M, Kikkawa F, Ishikawa H, Tamakoshi K, Maeda O, Hasegawa N, Mizuno K, Suzuki A, Itakura A, Nakashima N
Department of Obstetrics and Gynecology, Nagoya University School of Medicine, Japan.
Gynecol Oncol. 1994 Aug;54(2):209-14. doi: 10.1006/gyno.1994.1195.
To investigate the clinical significance of transvaginal color-pulse Doppler sonography in ovarian tumors, 109 patients were examined at Nagoya University Hospital. Ultrasonographic patterns were classified and the levels of three circulating tumor markers, CA125, CA72-4, and CA19-9, were simultaneously evaluated. In differentiating benign and malignant ovarian tumors, transvaginal color-pulse Doppler and ultrasonographic pattern classification were superior to the tumor markers. Of 49 cases with benign pattern, 45 were benign (91.8%). Of 60 cases with malignant pattern, 24 (40%) were benign and 36 (60%) were malignant or borderline malignant. In this group color-pulse Doppler sonography was the most useful procedure, and sensitivity, specificity, and accuracy were 75.0, 79.2, and 76.7%, respectively. Menopausal status and site of the arterial wave form in the tumor were also important. Transvaginal color-pulse Doppler sonography was a reliable diagnostic method for differentiating ovarian tumors.
为研究经阴道彩色脉冲多普勒超声检查在卵巢肿瘤中的临床意义，名古屋大学医院对109例患者进行了检查。对超声图像模式进行分类，并同时评估三种循环肿瘤标志物CA125、CA72 - 4和CA19 - 9的水平。在鉴别卵巢良恶性肿瘤方面，经阴道彩色脉冲多普勒超声检查和超声图像模式分类优于肿瘤标志物。49例表现为良性模式的病例中，45例为良性（91.8%）。60例表现为恶性模式的病例中，24例（40%）为良性，36例（60%）为恶性或交界性恶性。在该组中，彩色脉冲多普勒超声检查是最有用的检查方法，其敏感性、特异性和准确性分别为75.0%、79.2%和76.7%。绝经状态和肿瘤内动脉波形的位置也很重要。经阴道彩色脉冲多普勒超声检查是鉴别卵巢肿瘤的可靠诊断方法。
