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一名63岁女性因水痘相关暴发性肝炎接受肝移植。

Chickenpox-associated fulminant hepatitis that led to liver transplantation in a 63-year-old woman.

作者信息

Roque-Afonso Anne-Marie, Bralet Marie-Pierre, Ichai Philippe, Desbois Delphine, Vaghefi Parissa, Castaing Denis, Samuel Didier, Dussaix Elisabeth

机构信息

INSERM U785, Villejuif, France.

出版信息

Liver Transpl. 2008 Sep;14(9):1309-12. doi: 10.1002/lt.21514.

DOI:10.1002/lt.21514
PMID:18756459
Abstract

A 63-year-old woman treated with prednisone for sinusitis developed fulminant liver failure due to a clinically unsuspected primary varicella zoster virus infection. The diagnosis of herpetic hepatitis was made from a liver biopsy, and varicella zoster virus viremia was detected by polymerase chain reaction. She was treated successfully with transplantation and perioperative administration of acyclovir.

摘要

一名63岁女性因鼻窦炎接受泼尼松治疗，却因临床上未被怀疑的原发性水痘带状疱疹病毒感染而发展为暴发性肝衰竭。通过肝活检确诊为疱疹性肝炎，并通过聚合酶链反应检测到水痘带状疱疹病毒血症。她接受了移植手术及围手术期阿昔洛韦治疗，最终成功治愈。

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