Zhao Dong-Bing, Wang Yi, Shan Yi, Wang Cheng-Feng, Shao Yong-Fui, Zhao Ping
Department of Abdominal Surgical Oncology, Cancer Hospital (Institute), Chinese Academy of Medical Sciences, Beijing 100021, China.
Zhonghua Zhong Liu Za Zhi. 2008 Mar;30(3):231-3.
To investigate the clinical value of intraoperative aspiration cytology and histopathologic biopsy in the diagnosis of pancreatic cancer.
142 patients with suspected pancreatic carcinoma underwent surgical exploration and the data were retrospectively analyzed. Chi-square test (chi2) was used to compare the accuracy between fine-needle aspiration cytology and histopathologic biopsy.
Of the 192 patients with suspected pancreatic carcinoma, 80 were confirmed by histological biopsy and 87 by fine-needle aspiration cytology, with an accuracy rate of 83.8% and 93.1%, respectively. There was a statistically significant difference between these two groups (P = 0.027). No perioperative surgical complication was observed in this series.
Intraoperative aspiration cytology and histopathologic biopsy was safe and helpful with a high accuracy for the diagnosis of pancreatic carcinoma.
探讨术中细针穿刺细胞学检查及组织病理学活检在胰腺癌诊断中的临床价值。
对142例疑似胰腺癌患者进行手术探查,并对数据进行回顾性分析。采用卡方检验(χ²)比较细针穿刺细胞学检查与组织病理学活检的准确性。
在192例疑似胰腺癌患者中,80例经组织学活检确诊,87例经细针穿刺细胞学检查确诊,准确率分别为83.8%和93.1%。两组之间存在统计学显著差异(P = 0.027)。本系列未观察到围手术期手术并发症。
术中细针穿刺细胞学检查及组织病理学活检安全且有助于诊断胰腺癌,准确性高。