Intraoperative cytology of pancreatic masses. A 10-year experience.

The results of intraoperative fine needle aspiration biopsy (FNAB) of 92 pancreatic masses (1982-1992) are reported. The high sensitivity (1.00) and specificity (1.00) values are believed to be due to the presence of a cytopathologist in the operating room. The cytopathologist assesses the adequacy of the sampled material and, using rapid staining, can make a cytologic intraoperative diagnosis. This procedure led to the diagnosis of inflammatory lesions and of common and rare pancreatic neoplasms in a few minutes. Emphasis is laid on the characteristics of pancreatic FNAB vs. the more invasive procedures (e.g., wedge biopsies).