Magne S, Auger L, Bordy J M, de Carlan L, Isambert A, Bridier A, Ferdinand P, Barthe J
CEA, LIST, Laboratoire de Mesures Optiques, F-91191 Gif-sur-Yvette, France.
Radiat Prot Dosimetry. 2008;131(1):93-9. doi: 10.1093/rpd/ncn226. Epub 2008 Aug 30.
This article proposes an innovative multichannel optically stimulated luminescence (OSL) dosemeter for on-line in vivo dose verification in radiation therapy. OSL fibre sensors incorporating small Al(2)O(3):C fibre crystals (TLD(500)) have been tested with an X-ray generator. A reproducible readout procedure should reduce the fading-induced uncertainty ( approximately - 1% per decade). OSL readouts are temperature-dependent [ approximately 0.3% K(-1) when OSL stimulation is performed at the same temperature as irradiation; approximately 0.16% K(-1) after thermalisation (20 degrees C)]. Sensor calibration and depth-dose measurements with electron beams have been performed with a Saturne 43 linear accelerator in reference conditions at CEA-LNHB (ionising radiation reference laboratory in France). Predosed OSL sensors show a good repeatability in multichannel operation and independence versus electron energy in the range (9, 18 MeV). The difference between absorbed doses measured by OSL and an ionisation chamber were within +/-0.9% (for a dose of about 1 Gy) despite a sublinear calibration curve.
本文提出了一种创新的多通道光激励发光（OSL）剂量计，用于放射治疗中的在线体内剂量验证。已使用X射线发生器对包含小的Al(2)O(3):C纤维晶体（TLD(500)）的OSL光纤传感器进行了测试。一种可重复的读出程序应能减少由衰减引起的不确定性（每十年约-1%）。OSL读出值与温度有关[当OSL刺激在与辐照相同的温度下进行时，约为0.3% K(-1)；热化（20摄氏度）后约为0.16% K(-1)]。已在法国CEA-LNHB（法国电离辐射参考实验室）的参考条件下，使用一台Saturne 43直线加速器对预剂量的OSL传感器进行了电子束传感器校准和深度剂量测量。预剂量的OSL传感器在多通道操作中显示出良好的重复性，并且在（9、18 MeV）范围内与电子能量无关。尽管校准曲线呈次线性，但通过OSL测量的吸收剂量与电离室测量的吸收剂量之间的差异在+/-0.9%以内（对于约1 Gy的剂量）。
