Yukihara E G, Yoshimura E M, Lindstrom T D, Ahmad S, Taylor K K, Mardirossian G
Department of Physics, Oklahoma State University, Stillwater, 74078, USA.
Phys Med Biol. 2005 Dec 7;50(23):5619-28. doi: 10.1088/0031-9155/50/23/014. Epub 2005 Nov 16.
The potential of using the optically stimulated luminescence (OSL) technique with aluminium oxide (Al(2)O(3):C) dosimeters for a precise and accurate estimation of absorbed doses delivered by high-energy photon beams was investigated. This study demonstrates the high reproducibility of the OSL measurements and presents a preliminary determination of the depth-dose curve in water for a 6 MV photon beam from a linear accelerator. The uncertainty of a single OSL measurement, estimated from the variance of a large sample of dosimeters irradiated with the same dose, was 0.7%. In the depth-dose curve obtained using the OSL technique, the difference between the measured and expected doses was < or =0.7% for depths between 1.5 and 10 cm, and 1.1% for a depth of 15 cm. The readout procedure includes a normalization of the response of the dosimeter with respect to a reference dose in order to eliminate variations in the dosimeter mass, dosimeter sensitivity, and the reader's sensitivity. This may be relevant for quality assurance programmes, since it simplifies the requirements in terms of personnel training to achieve the precision and accuracy necessary for radiotherapy applications. We concluded that the OSL technique has the potential to be reliably incorporated in quality assurance programmes and dose verification.
研究了使用光激发发光(OSL)技术结合氧化铝(Al(2)O(3):C)剂量计精确准确估算高能光子束所传递吸收剂量的潜力。本研究证明了OSL测量具有高重现性,并给出了直线加速器6兆伏光子束在水中的深度剂量曲线的初步测定结果。根据用相同剂量照射的大量剂量计样本的方差估算,单次OSL测量的不确定度为0.7%。在使用OSL技术获得的深度剂量曲线中,对于1.5至10厘米深度,测量剂量与预期剂量之间的差异≤0.7%,对于15厘米深度,差异为1.1%。读出程序包括将剂量计的响应相对于参考剂量进行归一化,以消除剂量计质量、剂量计灵敏度和读取器灵敏度的变化。这对于质量保证计划可能是相关的,因为它简化了人员培训方面的要求,以实现放射治疗应用所需的精度和准确性。我们得出结论,OSL技术有潜力可靠地纳入质量保证计划和剂量验证。