Masharawi Y, Kjaer P, Bendix T, Manniche C, Wedderkopp N, Sorensen J S, Peled N, Jensen T S
Spinal Research Laboratory, Department of Physical Therapy, The Stanley Steyer School of Health Professions, Sackler Faculty of Medicine, Tel Aviv University, Israel.
Spine (Phila Pa 1976). 2008 Sep 1;33(19):2094-100. doi: 10.1097/BRS.0b013e31817f19f7.
Quantitative lumbar magnetic resonance imaging (MRI) measurements in children were taken twice and analyzed for intra- and intertester reproducibility.
To evaluate the reproducibility of a variety of lumbar quantitative measurements taken from MRIs of children from the general population.
The reproducibility of lumbar quantitative measurements has never been tested on MRIs of children from the general population. This is a prerequisite for a reliable anatomic characterization of the immature spine in normal and pathologic conditions.
Lumbar quantitative measurements from 40 T2-weighted lumbar (L1-S1) MRIs of children from the general population were taken twice by 1 tester for intratester reproducibility and compared with the same measurements (L4-S1) of the same MRIs taken by a second tester for intertester reproducibility. The following parameters were measured using the iQ-VIEW system (IMAGE Information Systems Ltd., version 1.2.2, Plauen, Germany): Linear measurements--zygoappophyseal facets and interfacet widths, and vertebral body (VB), pedicle and intervertebral discs heights, widths, and lengths. Angular measurements--zygoappophyseal tranverse superior facet angles, sagittal VB, and disc wedging, lumbar lordosis, and sacral inclination. Statistical analysis included the concordance correlation coefficient (CCC), and Bland and Altman's limits of agreement (LOA).
A total of 6160 measurements were analyzed. Good to excellent intratester reproducibility (0.75 < or =CCC < or =0.99) was indicated for all linear measurements (except for pedicle heights) (LOA: -4.76; 5.74 mm) and for angular measurements related to the facets orientation, lumbar lordosis, and sacral inclination (LOA: 11.22 degrees ; 12.34 degrees). VB and disc sagittal wedging manifested poor intratester reproducibility (CCC < 0.75). Good to excellent intertester reproducibility was indicated for 70% of all linear measurements (LOA: -5.83; 4.59 mm) and for all angular measurements in the lumbar spine (L4-S1) (LOA: -9.96 degrees ; 14.62 degrees) except for VB and disc sagittal wedging at L5 (CCC < 0.75).
Quantitative lumbar MRI measurements in children from the general population were found to be reproducible indicating a good visualization of immature vertebral anatomic margins on MRIs and an accurate definition of the measurement protocol.
对儿童进行腰椎磁共振成像（MRI）定量测量，共进行两次，并分析测量者内和测量者间的可重复性。
评估从普通人群儿童的MRI中获取的各种腰椎定量测量的可重复性。
腰椎定量测量的可重复性从未在普通人群儿童的MRI上进行过测试。这是在正常和病理条件下对未成熟脊柱进行可靠解剖特征描述的前提条件。
由一名测量者对40例普通人群儿童的T2加权腰椎（L1-S1）MRI进行两次腰椎定量测量，以评估测量者内的可重复性，并与另一名测量者对相同MRI进行的相同测量（L4-S1）进行比较，以评估测量者间的可重复性。使用iQ-VIEW系统（德国普劳恩IMAGE信息系统有限公司，版本1.2.2）测量以下参数：线性测量——关节突关节面和关节面间宽度，以及椎体（VB）、椎弓根和椎间盘的高度、宽度和长度。角度测量——关节突横向上关节面角度、矢状位VB和椎间盘楔形变、腰椎前凸和骶骨倾斜度。统计分析包括一致性相关系数（CCC）以及布兰德和奥特曼一致性界限（LOA）。
共分析了6160次测量。所有线性测量（椎弓根高度除外）（LOA：-4.76；5.74mm）以及与关节面方向、腰椎前凸和骶骨倾斜度相关的角度测量（LOA：11.22°；12.34°）显示出良好至优秀的测量者内可重复性（0.75≤CCC≤0.99）。VB和椎间盘矢状位楔形变表现出较差的测量者内可重复性（CCC<0.75）。所有线性测量的70%（LOA：-5.83；4.59mm）以及腰椎（L4-S1）的所有角度测量（LOA：-9.96°；14.62°）显示出良好至优秀的测量者间可重复性，L5处的VB和椎间盘矢状位楔形变除外（CCC<0.75）。
发现普通人群儿童的腰椎MRI定量测量具有可重复性，这表明MRI上未成熟椎体解剖边缘的可视化良好，且测量方案的定义准确。
