Enders Dieter, Han Jianwei, Henseler Alexander
Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074, Aachen, Germany.
Chem Commun (Camb). 2008 Sep 14(34):3989-91. doi: 10.1039/b809913h. Epub 2008 Jul 25.
The asymmetric intermolecular Stetter reaction is catalyzed by a novel triazolium salt derived N-heterocyclic carbene leading to 1,4-diketones in moderate to excellent yields (49-98%) and moderate to good enantioselectivities (56-78% ee), which could be enhanced by one recrystallization to excellent levels (90-99% ee).
一种新型三唑鎓盐衍生的N-杂环卡宾催化不对称分子间施陶丁格反应，以中等至优异的产率（49 - 98%）和中等至良好的对映选择性（56 - 78% ee）生成1,4 - 二酮，通过一次重结晶可将对映选择性提高到优异水平（90 - 99% ee）。
